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Mitochondrial complex III is required for hypoxia-induced ROS production and cellular oxygen sensing

Abstract Multicellular organisms initiate adaptive responses when oxygen (O2) availability…

Cerebral microvascular changes in permeability and tight junctions induced by hypoxia-reoxygenation

Abstract Mark, Karen S., and Thomas P. Davis. Cerebral microvascular…

Assessment of Cellular Oxygen Gradients with a Panel of Phosphorescent Oxygen-Sensitive Probes

Abstract The supply of oxygen (O2) to respiring tissue, cells,…

An E3 Ligase Possessing an Iron-Responsive Hemerythrin Domain Is a Regulator of Iron Homeostasis

Abstract Cellular iron homeostasis is maintained by the coordinate posttranscriptional…

Ambient Oxygen Promotes Tumorigenesis

Abstract Oxygen serves as an essential factor for oxidative stress,…

Hypoxic Induction of Interleukin-8 Gene Expression in Human Endothelial Cells

Abstract Because leukocyte-mediated tissue damage is an important component of…

Hypoxia-inducible Factor-1-dependent Regulation of the Multidrug Resistance ( MDR1) Gene

Abstract The microenvironment of rapidly growing tumors is associated with…

Superiority of Small Islets in Human Islet Transplantation

Abstract Many factors influence the outcome of islet transplantation. As…

Supporting Online Material for An E3 Ligase Possessing an Iron-Responsive Hemerythrin Domain Is a Regulator of Iron Homeostasis

Abstract Non-tumorigenic immortalized human bronchial epithelial HBEC-30 cells ((S1); kindly…

System for exposing cultured cells to intermittent hypoxia utilizing gas permeable cultureware

Abstract Tissue intermittent hypoxia (IH) occurs in obstructive sleep apnea,…

FLIP Protects against Hypoxia/Reoxygenation-Induced Endothelial Cell Apoptosis by Inhibiting Bax Activation

Abstract Hypoxia/reoxygenation causes cell death, yet the underlying regulatory mechanisms…

Translational repression during chronic hypoxia is dependent on glucose levels

Abstract Translation is often repressed in cell lines that are…

Hypoxia sensitization of hepatocytes to neutrophil elastase-mediated cell death depends on MAPKs and HIF-1α

Abstract Sparkenbaugh EM, Ganey PE, Roth RA. Hypoxia sensitization of…

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