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Research Citations

Functional hypoxia drives neuroplasticity and neurogenesis via brain erythropoietin

Abstract Erythropoietin (EPO), named after its role in hematopoiesis, is…

Wireless, battery-free optoelectronic systems as subdermal implants for local tissue oximetry

Abstract Monitoring regional tissue oxygenation in animal models and potentially…

System for exposing cultured cells to intermittent hypoxia utilizing gas permeable cultureware

Abstract Tissue intermittent hypoxia (IH) occurs in obstructive sleep apnea,…

Brain erythropoietin fine-tunes a counter balance between neurodifferentiation and microglia in the adult hippocampus

Abstract In adult cornu ammonis hippocampi, erythropoietin (EPO) expression drives…

Hypoxia Rescues Frataxin Loss by Restoring Iron Sulfur Cluster Biogenesis

Abstract Friedreich’s ataxia (FRDA) is a devastating, multisystemic disorder caused…

Ambient Oxygen Promotes Tumorigenesis

Abstract Oxygen serves as an essential factor for oxidative stress,…

Myocardial Hypertrophy Overrides the Angiogenic Response to Hypoxia

Abstract Background: Cyanosis and myocardial hypertrophy frequently occur in combination.…

Chronic Intermittent Hypoxia Elicits Serotonin-Dependent Plasticity in the Central Neural Control of Breathing

Abstract We tested the hypothesis that chronic intermittent hypoxia (CIH)…

150-kDa Oxygen-regulated Protein (ORP150) Suppresses Hypoxia-induced Apoptotic Cell Death*

Abstract To determine the contribution of 150-kDa oxygen-regulated protein (ORP150)…