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Intermittent hypoxia regulates RNA polymerase II in hippocampus and prefrontal cortex

Abstract Intermittent hypoxia (IH) is a major pathological factor in…

Nitric Oxide Is a Factor in the Stabilization of Hypoxia-Inducible Factor-1 α in Cancer: Role of Free Radical Formation

Abstract Widespread expression of the A-subunit of hypoxia-inducible factor (HIF-1A)…

Mitochondrial complex III is required for hypoxia-induced ROS production and cellular oxygen sensing

Abstract Multicellular organisms initiate adaptive responses when oxygen (O2) availability…

eIF2α Kinase PKR Modulates the Hypoxic Response by Stat3-Dependent Transcriptional Suppression of HIF-1 α

Abstract Hypoxia within the tumor microenvironment promotes angiogenesis, metabolic reprogramming,…

Hypoxia-inducible factor and nuclear factor kappa-B activation in blood–brain barrier endothelium under hypoxic/reoxygenation stress

Abstract This investigation focuses on transcription factor involvement in blood–brain…

Effects of reduced mucus oxygen concentration in airway Pseudomonas infections of cystic fibrosis patients

Abstract Current theories of CF pathogenesis predict different predisposing “local…

A Functional Role for Sodium-Dependent Glucose Transport across the Blood-Brain Barrier during Oxygen Glucose Deprivation

Abstract In the current study, we determined the functional significance…

Regulation of Tumor Angiogenesis by Oxygen-regulated Protein 150, an Inducible Endoplasmic Reticulum Chaperone

Abstract Expression of angiogenic factors such as vascular endothelial growth…

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