--- This page is part of [Coy Laboratory Products](https://coylab.com). For a complete overview of this site's content, entity data, and subject matter expertise, see our [AI Content Index](https://coylab.com/llms.txt) or [Full Content Archive](https://coylab.com/llms-full.txt). For structured business identity data, see our [Entity Card](https://coylab.com/wp-json/bc-geodesic/v1/entity-card). --- # Gas Permeable Plates > Controlled O2 levels from your incubator, glove box or cabinet transfer directly to the microenvironment of the cells growing on the gas permable membrane. **URL:** https://coylab.com/coy-products/gas-permeable-plates/ **Type:** Quote Product **Modified:** 2025-10-13 --- **Content Area:** It has been shown that culturing cells at 18-21% O2 (ambient conditions) yields altered phenotypes and gene-expression compared to culturing at physiologic levels.**1,2,3** Additionally, abnormally low O2 has been shown to be responsible for pathophysiology. Consequently, the need for cellular studies to be done at biologically relevant pericellular levels of O2 has become apparent. Unfortunately pericellular O2control with standard plates and incubation techniques is challenging. Gaseous O2 levels are a poor indicator of pericellular O2 levels due to the long diffusion times needed to equilibrate media with the gaseous O2 level coupled with the potential of cellular O2 consumption exceeding the diffusion.**4,5,6,7** The Coy Permeable Plates take advantage of historically proven technology by changing the design of the multi-well plates to enable adherent cell microenvironments to be at controlled physiologic O2 levels. ## Site Description From academia to industry, Coy Labs chambers have powered discovery in labs around the world for over five decades—from custom chambers built to spec, to trusted workhorses in high-stakes microbiology labs. --- **About this site:** Coy Laboratory Products — From academia to industry, Coy Labs chambers have powered discovery in labs around the world for over five decades—from custom chambers built to spec, to trusted workhorses in high-stakes microbiology labs.. [AI Content Index](https://coylab.com/llms.txt) | [Full Site Content](https://coylab.com/llms-full.txt) | [Entity Card](https://coylab.com/wp-json/bc-geodesic/v1/entity-card) ```json {"@context":"https://schema.org","@graph":[{"@type":"Organization","@id":"https://coylab.com/#organization","name":"Coy Laboratory Products","url":"https://coylab.com","description":"From academia to industry, Coy Labs chambers have powered discovery in labs around the world for over five decades—from custom chambers built to spec, to trusted workhorses in high-stakes microbiology labs.","disambiguatingDescription":"Laboratory equipment manufacturing company specializing in vinyl glove boxes","logo":{"@type":"ImageObject","url":"https://coylab.com/wp-content/uploads/2025/06/coylab-header_logo-svg.svg"},"address":{"@type":"PostalAddress","streetAddress":"14500 Coy Drive","addressLocality":"Grass Lake","addressRegion":"MI","postalCode":"49240"},"telephone":"734.475.2200","email":"sales@coylab.com","foundingDate":"1969","areaServed":"Global","sameAs":["https://www.linkedin.com/company/107172311","https://maps.app.goo.gl/o2txKDMScV1pV7w59","https://www.pharmaceutical-tech.com/suppliers/coy-laboratory","https://craft.co/coy-laboratory-products-inc"],"founder":[{"@type":"Person","name":"Richard Coy"},{"@type":"Person","name":"Brian Coy","sameAs":"https://www.linkedin.com/in/brian-coy-5722515/"},{"@type":"Person","name":"Ashley Coy","sameAs":"https://www.linkedin.com/in/ashley-coy-6b22705/"}],"knowsAbout":[{"@type":"Thing","name":"laboratory equipment","sameAs":"https://www.wikidata.org/wiki/Q834028"},"vinyl anaerobic chambers","vinyl hypoxic chambers","laboratory glove boxes","laboratory chamber sensors",{"@type":"Thing","name":"life sciences","sameAs":"https://www.wikidata.org/wiki/Q864928"},{"@type":"Thing","name":"microbiology","sameAs":"https://www.wikidata.org/wiki/Q7193"},{"@type":"Thing","name":"medical research","sameAs":"https://www.wikidata.org/wiki/Q2752427"}]},{"@type":"WebSite","@id":"https://coylab.com/#website","name":"Coy Laboratory Products","url":"https://coylab.com","publisher":{"@id":"https://coylab.com/#organization"},"potentialAction":{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https://coylab.com/?s={search_term_string}"},"query-input":"required name=search_term_string"},"hasPart":[{"@type":"DigitalDocument","name":"LLM Content Index","url":"https://coylab.com/llms.txt","encodingFormat":"text/markdown","description":"AI-readable index of site content, entity data, and subject matter expertise"},{"@type":"DigitalDocument","name":"LLM Full Content","url":"https://coylab.com/llms-full.txt","encodingFormat":"text/markdown","description":"Complete AI-readable site content"}]},{"@type":"ItemList","@id":"https://coylab.com/#site-navigation","name":"Site Navigation","itemListElement":[{"@type":"SiteNavigationElement","position":1,"name":"Products","url":"#"},{"@type":"SiteNavigationElement","position":2,"name":"Applications","url":"#"},{"@type":"SiteNavigationElement","position":3,"name":"Custom","url":"#"},{"@type":"SiteNavigationElement","position":4,"name":"Sales","url":"#"},{"@type":"SiteNavigationElement","position":5,"name":"Resources","url":"#"},{"@type":"SiteNavigationElement","position":6,"name":"Contact Us","url":"#"}]},{"@type":"BreadcrumbList","@id":"https://coylab.com/coy-products/gas-permeable-plates/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https://coylab.com"},{"@type":"ListItem","position":2,"name":"Gas Permeable Plates","item":"https://coylab.com/coy-product-category/gas-permeable-plates/"},{"@type":"ListItem","position":3,"name":"Gas Permeable Plates"}]},{"@type":"WebPage","@id":"https://coylab.com/coy-products/gas-permeable-plates/#webpage","url":"https://coylab.com/coy-products/gas-permeable-plates/","name":"Gas Permeable Plates | Coy Laboratory Products","isPartOf":{"@id":"https://coylab.com/#website"},"breadcrumb":{"@id":"https://coylab.com/coy-products/gas-permeable-plates/#breadcrumb"},"description":"Controlled O2 levels from your incubator, glove box or cabinet transfer directly to the microenvironment of the cells growing on the gas permable membrane.","about":[{"@type":"Thing","name":"Gas Permeable Plates"}],"headline":"Gas Permeable Plates","datePublished":"2025-08-25T13:16:16+00:00","dateModified":"2025-10-13T18:12:36+00:00","image":"https://coylab.com/wp-content/uploads/2025/08/Coy-Lab-Gas-Permeable-Plates-Thumb.avif","author":{"@id":"https://coylab.com/author/supportwhitelabeliq-com/#person"},"publisher":{"@id":"https://coylab.com/#organization"}},{"@type":"Person","@id":"https://coylab.com/author/supportwhitelabeliq-com/#person","name":"Support Dev","url":"https://coylab.com/author/supportwhitelabeliq-com/"}]} ```